Pharmaceutical Engineering

High-performance engineering simulations and technical consulting delivering measurable business impact, reduced risk and accelerated innovation.

Engineering Excellence That Drives Results

At SIM-engineer, we apply engineering principles to the design, development, and production of safe and effective drugs and pharmaceutical products.

Why SIM-engineer?

Risk Reduction

Validated numerical models supporting confident engineering decisions and regulatory compliance.

Cost Optimisation

Minimised prototyping and improved design efficiency through advanced simulation workflows.

Accelerated Development

Faster time-to-market enabled by integrated multiphysics and digital engineering tools.

Pharmaceutical Engineering

We provide comprehensive process engineering services dedicated to supporting the development, optimization, and scale-up of pharmaceutical manufacturing operations. Our team delivers advanced simulation based analyses that enhance process understanding, improve product quality, and reduce development time for both laboratory and industrial-scale systems.

We specialize in the application of Computational Fluid Dynamics (CFD) and Discrete Element Method (DEM) to accurately simulate complex pharmaceutical processes involving multiphase flow, particle dynamics, heat and mass transfer, and equipment–material interactions. Using CFD, we analyze airflow patterns, temperature distribution, humidity transport, and fluidization behavior in systems such as fluidized beds, dryers, coaters, and granulators. DEM enables us to model particle motion, mixing, segregation, compaction, and coating uniformity—providing deep insight into processes such as tableting, compaction, roller compaction, powder flow, and coating performance.

By integrating CFD and DEM, we offer precise predictions of process efficiency, uniformity, residence times, coating thickness distribution, and mechanical stresses on particles. These models support the design and optimization of equipment and operating conditions, ensuring consistent product quality and robust process performance.

With extensive expertise in pharmaceutical process engineering, we assist clients throughout the entire development and scale-up cycle from early stage feasibility studies and parameter sensitivity analysis, through detailed virtual prototyping, to supporting pilot-scale and full-scale implementation. Our approach reduces experimental workload, shortens development timelines, and increases confidence in process robustness during technology transfer and commercial production.

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